Use of cDNA Tiling Arrays for Identifying Protein Interactions Selected by In Vitro Display Technologies
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چکیده
منابع مشابه
Use of cDNA Tiling Arrays for Identifying Protein Interactions Selected by In Vitro Display Technologies
In vitro display technologies such as mRNA display are powerful screening tools for protein interaction analysis, but the final cloning and sequencing processes represent a bottleneck, resulting in many false negatives. Here we describe an application of tiling array technology to identify specifically binding proteins selected with the in vitro virus (IVV) mRNA display technology. We construct...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0001646